Opportunity Information: Apply for RFA AG 25 025

This NIH funding opportunity (RFA-AG-25-025) supports education-focused short courses under the R25 mechanism that train researchers to do cross-national comparative analyses using cognitive data from the Health and Retirement Study (HRS) International Family of Studies (often called the International HRS) and the Harmonized Cognitive Assessment Protocol (HCAP). The overall purpose is capacity-building: helping participants learn how to access, understand, manage, and analyze these harmonized and comparable cognitive datasets across countries so they can produce stronger research on aging and Alzheimers disease and Alzheimers disease-related dementias (AD/ADRD). The emphasis is on practical skills that increase actual utilization of these cognitive measures in real cross-country research, not on running clinical trials (the announcement is explicitly "Clinical Trial Not Allowed").

The courses are expected to strengthen the field's ability to examine how differing national and local contexts shape cognitive aging, dementia risk, dementia progression, and caregiving experiences. A central idea behind the program is that cross-national data can reveal how policy environments, health systems, economic conditions, social structures, and cultural factors may lead to different AD/ADRD outcomes across populations. By training researchers to leverage internationally comparable HRS-family and HCAP cognitive data, the program aims to generate evidence that can inform interventions and policy decisions in the United States and internationally, with the longer-term goal of improving population health and outcomes related to dementia.

Priority topic areas are broad and include, but are not limited to, behavioral and social pathways to AD/ADRD; cognitive and dementia epidemiology; dementia care; caregiver and care partner research; the effects of unexpected environmental or economic shocks (for example, major recessions, disasters, or other disruptions) on cognitive health and dementia-related outcomes; individual-level protective factors that may reduce risk or support resilience; and statistical methods appropriate for cross-national comparative work. The notice clearly leaves room for other relevant aging and dementia questions, as long as they build meaningful analytic competence using International HRS and HCAP cognitive data and are aligned with the goal of improving cross-national research skills.

Eligible applicants span a wide range of U.S.-based organizations and government entities, including state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education in the categories specified); for-profit organizations other than small businesses; and small businesses. The notice also highlights other eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. While the opportunity supports cross-national research training, foreign organizations (non-U.S. entities) are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible to apply; however, foreign components are allowed as defined in the NIH Grants Policy Statement, which typically means certain international collaborations or elements may be included within an otherwise eligible U.S. application, consistent with NIH rules.

Administratively, this is a discretionary NIH grant opportunity in the health category (CFDA 93.866), using the grant funding instrument and the R25 activity code, which is commonly used for education and training programs such as courses, workshops, and other structured learning activities. The original application closing date listed is 2024-11-01. The listed award ceiling is $350,000. The goal of the funded activities is not simply to present information, but to measurably expand the community of researchers who can competently conduct cross-national analyses with these specific cognitive data resources, thereby accelerating rigorous, policy-relevant AD/ADRD research grounded in international comparisons.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Short Courses Promoting Cross-National Analyses Using Data from the International Health and Retirement Study (HRS) and Harmonized Cognitive Assessment Protocol (HCAP) (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
  • This funding opportunity was created on 2024-08-27.
  • Applicants must submit their applications by 2024-11-01. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $350,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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