Opportunity Information: Apply for RFA DA 19 029
The HEAL Initiative: HEALthy Brain and Child Development (HEALthy BCD) funding opportunity (RFA-DA-19-029) is a National Institutes of Health (NIH) grant mechanism designed to support early-stage, collaborative planning work to shape a large research effort focused on how substance exposure before and after birth affects children as they grow. Led by the National Institute on Drug Abuse (NIDA) in partnership with several NIH Institutes, Centers, and Programs (including NIAAA, NICHD, NIMH, NIMHD, NINDS, and ECHO), the program is aimed at developing and testing the feasibility of study designs that can realistically be carried out across multiple sites. The scientific focus includes a wide range of substances and patterns of exposure, such as opioids and opioid treatment medications, cannabis, alcohol, tobacco, and other prescription or illicit drugs, whether used alone or in combination. The ultimate outcomes of interest span brain development, social and behavioral development, later mental health challenges, and future substance use risk.
This opportunity uses a Collaborative R34 mechanism and is explicitly marked as Clinical Trial Not Allowed, meaning applicants are expected to focus on planning, design, and feasibility work rather than running clinical trials. In practice, that typically points to activities like refining recruitment strategies and eligibility criteria, assessing whether proposed measurements are workable in real-world settings, piloting data collection workflows, determining which developmental assessments and neurobehavioral measures are acceptable and reliable in the target populations, and establishing procedures that would allow data to be collected consistently across different locations. A key goal is to reduce uncertainty before launching a much larger, longer-term study by showing that the proposed methods can succeed, that families can be enrolled and retained, and that the research operations and governance structures can function across a network.
Beyond the technical design work, awardees are expected to take part in multiple grantee meetings. These meetings are intended to help teams compare what they are learning, align approaches where it makes sense, and start building the relationships and shared standards needed for a coordinated, multi-site research network. This networking component is a major feature of the announcement: NIH is not only funding isolated planning projects, but also actively setting the stage for an eventual broader consortium capable of conducting a large-scale study on prenatal and postnatal substance exposure and child development.
Eligibility is broad and includes many types of U.S.-based organizations and governments. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; and Native American tribal organizations other than federally recognized tribal governments. It also includes public housing authorities/Indian housing authorities, nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education), for-profit organizations other than small businesses, and small businesses. The announcement also highlights additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. At the same time, it places strict limits on foreign involvement: non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
Administratively, this is a discretionary NIH grant under activity areas that touch education, environment, health, and social services, and it is associated with multiple CFDA numbers (93.113, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865), reflecting the multi-Institute nature of the initiative. The listed award ceiling is $225,000, and the original closing date for the referenced announcement cycle was March 25, 2019 (with the opportunity created on December 21, 2018). Overall, the program is best understood as a targeted investment in the groundwork: building feasible, scalable, and harmonized study designs that can later support definitive research on how early-life substance exposures shape neurodevelopmental, behavioral, and mental health trajectories.Apply for RFA DA 19 029
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) (Collaborative R34- Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.242, 93.273, 93.279, 93.307, 93.853, 93.865.
- This funding opportunity was created on 2018-12-21.
- Applicants must submit their applications by 2019-03-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $225,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) Apply for PAR 19 134 Funding Number: PAR 19 134 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $300,000 |
| HEAL Initiative: HEALthy Brain and Child Development Study (HEALthy BCD) ( R34- Clinical Trial Not Allowed) Apply for RFA DA 19 036 Funding Number: RFA DA 19 036 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $225,000 |
| Limited Competition for a Connectome Coordination Facility (R24 Clinical Trial Not Allowed) Apply for RFA MH 20 210 Funding Number: RFA MH 20 210 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $900,000 |
| Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) Apply for RFA OD 19 016 Funding Number: RFA OD 19 016 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trials Required) Apply for RFA OD 19 018 Funding Number: RFA OD 19 018 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) Apply for RFA OD 19 015 Funding Number: RFA OD 19 015 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| PHS 2019-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required Apply for PA 19 273 Funding Number: PA 19 273 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Apply for PAR 19 276 Funding Number: PAR 19 276 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) Apply for PAR 19 274 Funding Number: PAR 19 274 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Marmoset Coordination Center (U24 Clinical Trials Not Allowed) Apply for RFA MH 20 150 Funding Number: RFA MH 20 150 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed) Apply for RFA MH 20 145 Funding Number: RFA MH 20 145 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint for Neuroscience Research Education Program on Translational Devices (R25 Clinical Trial Not Allowed) Apply for RFA NS 20 003 Funding Number: RFA NS 20 003 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $250,000 |
| NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP-ENDURE) (R25 Clinical Trial Not Allowed) Apply for RFA NS 20 015 Funding Number: RFA NS 20 015 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Trial Readiness (R21 Clinical Trial Not Allowed) Apply for RFA OD 20 004 Funding Number: RFA OD 20 004 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $200,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) Apply for PA 20 142 Funding Number: PA 20 142 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) Apply for PA 20 184 Funding Number: PA 20 184 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 189 Funding Number: PA 20 189 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 198 Funding Number: PA 20 198 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 204 Funding Number: PA 20 204 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required) Apply for PA 20 201 Funding Number: PA 20 201 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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