Opportunity Information: Apply for PA 20 205
The Mentored Patient-Oriented Research Career Development Award (Parent K23, Independent Clinical Trial Not Allowed) is an NIH career development grant designed to help early-career clinician-scientists build a strong, sustainable research trajectory in patient-oriented research. The core idea is to provide protected time, structured mentorship, and research support so that a clinically trained investigator with a doctoral-level clinical degree can deepen their research skills and transition toward research independence while staying focused on studies that directly involve human participants or data/materials of human origin tied to patient care and outcomes. In practice, this award is meant for people who have clearly committed their career direction to patient-oriented research and who would benefit from a mentored, career-development-focused award rather than a standard research project grant.
A key constraint in this specific K23 parent announcement is that an independent clinical trial is not allowed under this funding opportunity. That generally means the applicant cannot propose to lead their own standalone clinical trial as the primary, independently run trial. The work can still be patient-oriented and can involve clinical research activities, but the proposed project must fit the “independent clinical trial not allowed” policy for this announcement. Applicants who want to lead an independent clinical trial typically need to use a different NIH funding announcement that explicitly permits or requires clinical trials. This distinction matters because NIH routes applications through different review and policy pathways depending on whether the project meets NIH’s definition of a clinical trial and whether the applicant is proposing to run it independently.
The opportunity is administered by the National Institutes of Health (NIH) and uses the grant funding instrument. It is listed as a discretionary funding opportunity and falls under a broad set of health-related CFDA program areas (including multiple NIH institutes and centers), reflecting that K23 awards can support patient-oriented research across many diseases, conditions, and clinical disciplines. The funding opportunity number is PA-20-205, and the original closing date shown in the source information is 2024-05-07, indicating the notice has had scheduled due dates under this parent announcement structure.
Eligibility is intentionally broad on the institutional side. Eligible applicant organizations include many types of U.S.-based entities such as state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits (both 501(c)(3) and non-501(c)(3), other than institutions of higher education); for-profit organizations (other than small businesses); small businesses; and several tribal and housing authority categories, including federally recognized Native American tribal governments and other Native American tribal organizations. NIH also explicitly highlights additional eligible applicant types, including Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; and Indian/Native American tribal governments that are not federally recognized.
At the same time, there are important limits related to non-U.S. entities and components. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components may be allowed when they meet NIH’s definition in the NIH Grants Policy Statement, which typically means a U.S. applicant institution can include a justified foreign component if it offers unique resources, populations, expertise, or conditions not readily available in the United States and if it is clearly necessary to accomplish the scientific aims.
Overall, this K23 parent opportunity is best understood as a mentored career development pathway for clinician researchers who want to become independent investigators in patient-oriented research, supported by an NIH grant mechanism that emphasizes training, mentorship, and a coherent career development plan, while explicitly restricting applicants from proposing an independent clinical trial under this particular announcement.Apply for PA 20 205
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.361, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.859, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2020-05-11.
- Applicants must submit their applications by 2024-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants who have applied for this opportunity (PA 20 205) also looked into and applied for these:
| Funding Opportunity |
|---|
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) Apply for PA 20 203 Funding Number: PA 20 203 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 20 222 Funding Number: PA 20 222 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplement for Research on Dietary Supplements (Admin Supp-Clinical Trial Not Allowed) Apply for PA 20 227 Funding Number: PA 20 227 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 20 242 Funding Number: PA 20 242 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 20 246 Funding Number: PA 20 246 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 20 245 Funding Number: PA 20 245 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 20 248 Funding Number: PA 20 248 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) Apply for PA 20 251 Funding Number: PA 20 251 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 20 261 Funding Number: PA 20 261 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2020-2 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required) Apply for PA 20 262 Funding Number: PA 20 262 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2020-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) Apply for PA 20 260 Funding Number: PA 20 260 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2020-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) Apply for PA 20 265 Funding Number: PA 20 265 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 20 275 Funding Number: PA 20 275 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 21 051 Funding Number: PA 21 051 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 21 050 Funding Number: PA 21 050 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity) Apply for PA 21 052 Funding Number: PA 21 052 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 21 049 Funding Number: PA 21 049 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 21 048 Funding Number: PA 21 048 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) Apply for PAR 21 038 Funding Number: PAR 21 038 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed) Apply for PA 21 071 Funding Number: PA 21 071 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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