Opportunity Information: Apply for RFA IP 19 003

The grant opportunity titled "Understanding and Improving Immunization Services among Adult Hospital Inpatient and Observation/Clinical Decision Unit Settings" (Funding Opportunity Number RFA IP 19 003) is a CDC-led research funding initiative intended to strengthen how adult vaccines are delivered in hospital-based settings. It focuses specifically on two patient care environments that often have missed vaccination opportunities: traditional adult inpatient units and short-stay areas such as 24-hour observation units or clinical decision units. The overall intent is to support practical, real-world research that both documents what hospitals are currently doing for adult immunizations and tests interventions that can measurably improve vaccination delivery and coverage.

A central aim of the NOFO is to generate a clearer picture of existing vaccination practices and vaccination coverage among adults while they are hospitalized or under short-term observation care. This includes understanding workflows, clinical decision-making, screening and assessment practices, documentation habits, use of standing orders, how vaccines are ordered and administered, and where breakdowns occur that lead to patients not being assessed or vaccinated. The CDC is looking for work that clarifies current baseline performance and identifies barriers and facilitators within hospital systems, including operational constraints, provider roles, patient eligibility identification, data capture, and coordination with immunization information systems and outpatient follow-up.

The second major aim is intervention-oriented: applicants are expected to implement and evaluate one or more strategies designed to improve immunization service delivery and ultimately increase vaccine coverage among eligible adult patients in these hospital settings. The interventions should align with CDC's Standards for Adult Immunization Practices and cover all ACIP-recommended adult immunizations, meaning the work is not limited to a single vaccine. In practice, this points to approaches such as improving routine assessment of vaccination status, creating or strengthening provider recommendations, building reliable offering and administration processes, and ensuring accurate documentation and reporting. Evaluation is a required element, so projects should not only deploy an intervention but also measure its effectiveness, feasibility, and impact on vaccination uptake and service delivery processes.

This funding is offered as a cooperative agreement, which typically means the CDC expects substantial involvement during the project period, such as technical assistance, collaboration on approach, and ongoing communication about implementation and evaluation. The award ceiling is $500,000, and the CDC anticipated making two awards under this announcement. The opportunity falls under the health activity category and is associated with CFDA number 93.185.

Eligible applicants are broad and include multiple levels of government (state, county, city/township, and special district governments), public and state-controlled institutions of higher education, independent school districts, federally recognized tribal governments and other tribal organizations, public housing authorities/Indian housing authorities, and nonprofit organizations both with and without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories). The sponsoring agency is the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CDC). The NOFO was created on October 30, 2018, with an original application deadline of February 1, 2019, and applications were required to be submitted electronically by 5:00 p.m. Eastern Time on the due date.

In plain terms, this opportunity is about closing a persistent gap in adult immunization by leveraging hospital encounters as a reliable point for vaccination assessment and delivery. Hospitals and observation units see large volumes of adults, many of whom have chronic conditions or risk factors that make ACIP-recommended vaccines particularly important, yet immunization checks and vaccine administration are often inconsistent in these settings. The CDC is funding projects that can map current practice, fix weak points with targeted interventions, and produce evidence on what works to increase adult vaccination coverage during inpatient and short-stay observation care.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Understanding and Improving Immunization Services among Adult Hospital Inpatient and Observation/Clinical Decision Unit Settings" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.185.
  • This funding opportunity was created on Oct 30, 2018.
  • Applicants must submit their applications by Feb 01, 2019 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
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